QUANTITATIVE ANALYSIS OF CONTRAST-ENHANCED ULTRASOUND AND MAGNETIC RESONANCE IMAGING
Physics-driven modelling of cancer or cardiovascular dysfunctions remains a key goal. Information on the (micro)vascular structure will be extracted by multimodal spatiotemporal analysis of contrast-agent transport, exploiting the different pharmacokinetics of ultrasound and MRI contrast agents. The extraction of multiple features from noisy, low-resolution images connects to GC 1 and contributes to the multidimensionality required for GC 2. Moreover, novel nonlinear pharmacokinetic models will connect to GC 3, exploring the possibility to replace the model equations with dedicated encoders. In connection to GC 4, a novel class of ultrasound contrast agents opens up immense possibilities for super-resolution imaging, breaking the diffraction limit by super-localization of the individual sources.